ESR 03 : Roxane Ridolfo
Born and raised in France, Roxane has developed a passion for nanomedicine. Before graduating in 2016 with a MSc in Chemistry and Physics with a speciality in polymers and formulation from Ecole Nationale Supérieure de Chimie, Biologie et Physique de Bordeaux (Pessac, France), Roxane did two internships working on drug delivery systems. First, she worked in the Pr. Vincent Rotello’s group at UMASS (Amherst, Massachusetts, USA), where she developed polymer-based nanospheres for delivery applications (cancer therapy and biofilm treatment). Then, she joined the Pr. Jan van Hest’s group at the Radboud University (Nijmegen, The Netherlands), where she worked on biodegradable polymer-based micelles formulation and characterization for drug delivery to treat leukemia.
Nowadays, Roxane is a 2nd year-PhD student at TU/e (Eindhoven, The Netherlands), linked to Pr. Jan van Hest’s group. Her project is called Particle Shape Effect and takes part of the European framework NANOMED.
Project topic: Particle Shape Effect (ESR3)
The objective of this project is to establish the effect micelle and polymersome shape has on drug release and cell uptake. Different shapes lead to different interaction surfaces between cells and particles. This will affect cell uptake and particle biodistribution.
A focus will be made on retinal drug delivery. All particles are composed of biodegradable block copolymers and the degradation behavior will be investigated.
Jan van Hest
September 9th, 2016
- July 2016 Nanomed kick-off meeting
- May-June 2018 University of Helsinki
- May-June 2019 University of Helsinki
- September 2018 Imperial College London
- June 2019 ChemConnection (NL)