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ESR1: (POSITION FILLED) Polymersomes via direct hydration method; Radboud University (Nijmegen, The Netherlands)

At Radboud University, we perform research and educate students covering the full width of the academic spectrum. Our university is located on a green, modern campus with state-of-the-art facilities. The atmosphere on campus is open and personal, which stimulates colleagues to share their knowledge beyond the boundaries of their own discipline. It encourages all to look further, to see more. Thus, Radboud University contributes to the development of new perspectives, within science and within society. This makes Radboud University successful and of international importance.

Early Stage Researcher (PhD Candidate) for the NANOMED European Training Network

within the Marie Sklodowska Curie Programme (1,0 fte)

Application deadline: CLOSED

Responsibilities

Prof. Jan van Hest’s research group at Radboud University, Faculty of Science, Nijmegen in the Netherlands, offers a programme of training in the field of Bio-Organic Chemistry. The group’s target is to create bio-inspired materials and processes in order to combine the functionality of biological systems with the flexibility and robustness of synthetic structures, using a variety of synthetic techniques, such as protein engineering, peptide synthesis and controlled polymerization methods.  The NANOMED project will provide training across a wide range of disciplines including biology, pharmacology, chemistry and material sciences, ensuring interdisciplinary and intersectoral experience. You will be enrolled in Radboud University’s doctoral programme and will defend your PhD at the end of the project. The PhD research in the Netherlands will be conducted in English.

Early Stage Researcher 1: Polymersomes via direct hydration method

In this ESR-task a strategy will be followed to construct biodegradable polymer vesicles (polymersomes) as drug delivery vehicles. The polymersomes are assembled from poly(caprolactone)-poy(ethylene glycol) block copolymers using a straightforward and water-based route The molecular weight dependence of the block copolymers on polymersome formation, the scalability of the method and the size control that can be attained will be studied. The hydrophobic domain will be tailored via copolymerization to the desired degradation behaviour. Furthermore, a methodology for the introduction of biological targeting motifswill be developed Finally, the polymersomes will be assessed for their drug delivery efficacy.

Skills required: polymer chemistry, supramolecular chemistry, nanoscience; affinity with life sciences research.

Work environment

You will perform your PhD research in a multidisciplinary Initial Training Network (ITN) project called NANOMED.

What we expect from you

At the time of recruitment you must be in the first four years of your research career and have not yet been awarded a doctoral degree; You have excellent communication skills and are able to work efficiently in a team. Specific technical requirements are mentioned separately for the individual ESR descriptions. Recruitment is open to all nationalities, but because of mobility rules defined by the EU, at the time of recruitment, candidates must not have resided or carried out their main activity (work, studies, etc.) in the Netherlands for more than 12 months in the three years immediately prior to the reference date (compulsory national service and/or short stays such as holidays are not taken into account).

What we have to offer

  • employment: 1,0 fte;
  • the gross starting salary amounts to € 2,125 per month, and will increase to € 2,717 in the fourth year;
  • in addition to the salary: an 8 % holiday allowance and an 8.3 % end-of-year bonus;
  • duration of the contract: 4 years;
  • you will be classified as a PhD candidate in the Dutch university job-ranking system (UFO).

Are you interested in our excellent employment conditions?

Would you like to know more?

Are you interested?

You should upload your application (attn. of Ms. W. van der Pluijm) exclusively using the button ‘Apply’ on the RU vacancy website. Your application should include (and be limited to) the following attachments:

  • Letter of motivation
  • Curriculum Vitae

For more information on your application: +31 24 3652131.

No commercial propositions please.